New York City, 1978. The 20 blocks of pawnshop and dive bars between 8th Avenue and the Hudson River owned by the Irish mafia and known as Hell’s Kitchen was never the easiest place to live. Or the safest. But for mob wives Kathy, Ruby and Claire--played by Melissa McCarthy, Tiffany Haddish, and Elisabeth Moss--things are about to take a radical, dramatic turn. When their husbands are sent to prison by the FBI the women take business into their own hands, running the rackets and taking out the competition…literally.